Pharmacological actions and therapeutic uses of cannabis and cannabinoids

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Pharmacological actions and therapeutic uses of cannabis and cannabinoids.

This review highlights the pharmacology, pharmacokinetics, pharmacological actions, therapeutic uses and adverse effects of cannabinoids. The effect of cannabinoids on anaesthesia is mentioned briefly. Important advances have taken place in cannabinoid research over the last few years and have led to the discovery of novel ligands. The possible clinical applications of these ligands and the dir...

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Pharmacological actions of cannabinoids.

Mammalian tissues express at least two types of cannabinoid receptor, CB1 and CB2, both G protein coupled. CB1 receptors are expressed predominantly at nerve terminals where they mediate inhibition of transmitter release. CB2 receptors are found mainly on immune cells, one of their roles being to modulate cytokine release. Endogenous ligands for these receptors (endocannabinoids) also exist. Th...

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The therapeutic potential of cannabis and cannabinoids.

BACKGROUND Cannabis-based medications have been a topic of intense study since the endogenous cannabinoid system was discovered two decades ago. In 2011, for the first time, a cannabis extract was approved for clinical use in Germany. METHODS Selective literature review. RESULTS Cannabis-based medications exert their effects mainly through the activation of cannabinoid receptors (CB1 and CB...

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Medicinal Uses and Pharmacological Actions of Five Commonly Used Indian Medicinal Plants: A Mini-Review

Man depends heavily on various plant species for his survival. Indian traditional system of medicine is based on empirical knowledge of the observations and the experience over millennia and more than 5000 plants are used by different ethnic communities in India. During the last few decades there has been an increasing interest in the study of medicinal plants and their traditional use in diffe...

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Pharmacology and potential therapeutic uses of cannabis.

Throughout history, cannabis has been used as a natural therapeutic herb. Indeed the discovery of the remains of a young girl in Jerusalem who died in childbirth sometime around the third century AD, revealed residues of cannabis in the pelvic region. This strongly suggests that cannabis was used in medical practice in early human civilizations. Cannabis was first used as a medicine in Britain ...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 2001

ISSN: 0003-2409

DOI: 10.1111/j.1365-2044.2001.02269.x